The thought of curing cancer with limited metastatic
disease by resecting the primary and the metastatic lesions is becoming more common. Multilevel spondylectomy for resection of metastatic disease has been reported in the literature, mostly at the thoracic or lumbar level with some success. Reconstruction of the lumbosacral junction after tumor resection is a difficult endeavor and several techniques have been utilized. Subcutaneous anterior pelvic fixation has been described for the treatment of unstable pelvic fractures.
Review of the Grand Rounds case “”A novel Pelvic Ring Augmentation Construct for Lumbo-Pelvic Reconstruction in Tumour Surgery”" by Sathya Thambiraj, Daren Forward, James Thomas, Bronek Boszczyk and review of the pertinent literature.
The Transmembrane Transporters inhibitor authors describe a novel percutaneous rod technique and construct for buttressing a posterior spinal construct to a subcutaneous anterior pelvic fixator after tumor resection of the lumbo-pelvic
junction. They manage to salvage a difficult situation for which they should be commended. This technique may be useful in situations where instrumentation has to be preformed to the QNZ pelvis: i.e., in tumor reconstruction, fusions such as neuromuscular scoliotic disease to the pelvis, to augment a lumbo-pelvic construct when a nonunion occurs or in osteoporotic patients as a salvage procedure.”
“Three triterpenoids from the chloroform extract of the stem bark of Rhizophora mucronata (Rhizophoraceae) were isolated. The structures of these isolated compounds were identified by spectroscopic analysis as 3-O-(E)-(4-methoxy) cinnamoyl-15 -hydroxyl -amyrin (1), adian-5-en 3-ol (2) and lupeol (3).
Such compounds are being reported for the first time from this plant.”
“To provide the anatomical basis for the feasibility and clinical practice of lengthened sacroiliac screw fixation, by measuring various related indicators of the safe insertion regions of S1 and S2 lengthened sacroiliac screws.
A total of 66 healthy pelvises of adults were scanned by 64-slice spiral CT and the length, width and height of the safe insertion regions for S1 and S2 lengthened sacroiliac screw were measured. The safe screw entrance point locations were described with a quantitative method. The Ferroptosis inhibitor drugs indicators were recorded by descriptive statistics and the statistics of left and right sides, segments of S1 and S2, and different layers (including top, middle and bottom parts) of S1 and S2 were compared.
The lengths of ilium within the safe insertion regions for lengthened screws are more than 16 mm. The width and height of the safe insertion region of S1 and S2 are almost all more than 7.3 mm. Generally, the width and height of S1 are larger than those of S2. The reference ranges of the best/safest entrance point locations of lengthened sacroiliac screws are as follows-S1: 42.21-63.