It can degrade the extracellular matrix

leading to tumor metastasis.14 and 15 The plant combination (muthu marunthu) has been showed one of the common and notable features in poor growth rate of tumor cells. Also the muthu marunthu is combination plant biomass did not show any alteration of normal growing cells. The glycoproteins such as hexose, hexosamine, sialic acid and fucose are controlling the level in plasma by the treating of muthu marunthu (different plant extracts were formulated in various concentrations) fibrosarcoma rats. Hence muthu marunthu has very good controlling Carfilzomib price capacity on the biochemical events during tumor progression, without inducing any see more toxic effects for normal metabolism. 16 The aqueous extract of Iresine herbstii was synthesized silver nanoparticles was performed by green synthesis and plant mediated nanoparticles showed potent cytotoxicity against HeLa cancer cells. Plant synthesized silver nanoparticles have induced

over above 80% death of HeLa cell at a treatment of moderate concentration level is 300 mg/ml. The AgNPs are revealed a prominent activity of arrest metabolic function of fibroblast cells (IMR-90) at 400 mg concentration. The Persea americana Nigerian traditional plant extracts were used for the treatment of anticancer studies. The plant extracts contains polar compounds that were responsible for suppress the division of cancer cells. Since it is well known that the phytochemicals have been shown to induce cell cycle which it may cause apoptosis program. The secondary metabolites are affect the differentiation and proliferation of cells by the control of intracellular (ROS) reactive oxygen species on the electron transport chain and other metabolic pathway. These cytotoxic natural products play a vital role in breast and osteo cancer. The influences of anticancer activity were valid by Elaeis guineensis methanol extract against MCF-7 and vera cell line through by MTT assay. The presence of apoptotic bodies could also understand

in plant extract treated cancer cells. The cells whatever are also showed extensive vacuolation in the cytoplasm, indicating autophagy like mechanism of programmed cell death. 17 Sreelatha et al18 (2011) study demonstrates the ethanolic leaf extract of Sesbania grandiflora has potential activity against anticancer. The standard criteria of anticancer drug are suppress the protein synthesis metabolism as the same induces apoptosis function of the cells. However the treatment of S. grandiflora extracts were control the tumor cell volume and number of viable tumor cell. The minimum dose of S. grandiflora 200 mg/kg have been exhibit high activity against leukemia cells which may due to its extract and it contains nature composite of various phytochemicals that could counter act its toxicity.