Nelson – Advisory Committees or Review Panels: Merck; Grant/Research Support: Abbot, BMS, Beohringer Ingelheim, Gilead, Genentech, Merck, Bayer, Idenix, Vertex, Jansen Pietro Andreone – Advisory Committees or Review Panels: Roche, Janssen-Cilag, Gilead, MSD/Schering-Plough, Abbvie, Boehringer Ingelheim; Grant/Research Support: Roche, Gilead; Speaking and Teaching: Roche, MSD/Schering-Plough, Gilead Massimo Colombo – Advisory Committees or Review Panels: BRISTOL-MEY- ERS-SQUIBB, SCHERING-PLOUGH, ROCHE, GILEAD, BRISTOL-MEYERS-SQUIBB, SCHERING-PLOUGH, ROCHE, GILEAD, Janssen Cilag,
Achillion; Grant/ Research Support: BRISTOL-MEYERS-SQUIBB, ROCHE, GILEAD, BRISTOL-MEY-ERS-SQUIBB, Everolimus order ROCHE, GILEAD; Speaking and Teaching: Glaxo Smith-Kline, BRISTOL-MEYERS-SQUIBB, SCHERING-PLOUGH,
ROCHE, NOVARTIS, GILEAD, VERTEX, Glaxo Smith-Kline, BRISTOL-MEYERS-SQUIBB, SCHERING-PLOUGH, ROCHE, NOVARTIS, GILEAD, VERTEX, Sanofi Filipe Calinas Roscovitine chemical structure – Advisory Committees or Review Panels: Merck Sharp & Dohme, Roche Pharmaceuticals, Gilead sciences, AbbVie, Janssen; Consulting: Boeh-ringer Ingelheim; Speaking and Teaching: Bristol Myers Squibb, Gilead Sciences, Janssen; Stock Shareholder: Merck Sharpe Antonio Olveira – Speaking and Teaching: Gilead, BMS, MSD Dieter Häussinger – Consulting: Noxxon Pharma; Management Position: Dv^ssel-dorf University Press; Patent Held/Filed: Flicker Diagnostics GbR; Speaking and Teaching: Falk Pharma Simone I. Strasser – Advisory Committees or Review Panels: Janssen, AbbVie, Roche Products Australia, MSD, Bristol-Myers Squibb, Gilead, Norgine, Bayer Healthcare; Speaking and Teaching: Bayer Healthcare, Bristol-Myers Squibb, MSD, Roche Products Australia, Gilead, Janssen Tarik Asselah – Advisory Committees or Review Panels: AbbVie, Boerhinger-Ingelheim, Gilead, BMS, Roche, Janssen Curtis Cooper – Advisory Committees or Review Panels: Vertex, MERCK, Roche; Grant/Research Support: MERCK, Roche; Speaking and Teaching: Roche, MERCK Jerry O. Stern – Employment: Boehringer Ingelheim Wulf O. Boecher
– Employment: Boehringer Ingelheim GmbH George Kukolj – Employment: Boehringer Ingelheim Stella Aslanyan – Employment: Boehringer Ingelheim Pharmaceuticals Inc. Qiqi Deng – Employment: Boehringer Ingelheim Edward Wang – Employment: Boehringer Ingelheim Federico J. Mensa – Employment: Boehringer Ingelheim Atorvastatin The following people have nothing to disclose: Jean Delwaide, Denis Ouzan The purpose of this sub-study was to evaluate the pharmacoki-netics of asunaprevir (A), daclatasvir (D) and raltegravir (RAL), when combined to Peg-interferon/ribavirine (PR), in HIV-HCV co-infected patients receiving a RAL-based antiretroviral therapy. The first twenty patients (pts), previous null responders to PR, who were included in the ANRS HC30 study, participated in this pharmacokinetic sub-study. All pts were on RAL (400mg BID) combined with tenofovir and either emtricitabine (n=18) or abacavir (n=1) or emtricitabine+enfuvirtide (n=1).