Periodontol 2006, 42:80–87.CrossRef 8. Zijnge V, Ammann T, Thurnheer T, Gmür R: Subgingival GSK2879552 order biofilm structure. Edited by: Mombelli A, Kinane DF. Basel: Karger; 2012:1–16. [Frontiers of Oral Biology] 9. Shaddox LM, Alfant B, Tobler J, Walker C: Perpetuation of subgingival biofilms in an

in vitro model. Mol Oral Microbiol 2010, 25:81–87.PubMedCrossRef 10. Hope CK, Wilson M: Biofilm structure and cell vitality in a laboratory model Compound Library mouse of subgingival plaque. J Microbiol Methods 2006, 66:390–398.PubMedCrossRef 11. Guggenheim B, Gmür R, Galicia JC, Stathopoulou PG, Benakanakere MR, Meier A, Thurnheer T, Kinane DF: In vitro modeling of host-parasite interactions: the ‘subgingival’ biofilm challenge of primary human epithelial cells. BMC Microbiol 2009, 9:280.PubMedCrossRef 12. Guggenheim B, Giertsen E, Schupbach P, Shapiro S: Validation of an in vitro biofilm model of supragingival plaque. J Dent Res 2001, 80:363–370.PubMedCrossRef 13. Zijnge V, van Leeuwen MB, Degener JE, Abbas F, Thurnheer T, Gmür R, Harmsen HJ: Oral biofilm architecture on natural teeth. PLoS One 2010, 5:e9321.PubMedCrossRef 14. Kolenbrander PE, London J: Adhere today, here tomorrow: oral bacterial adherence. small molecule library screening J Bacteriol 1993, 175:3247–3252.PubMed 15. Ruiz V, Rodriguez-Cerrato V, Huelves L, Del Prado G, Naves P, Ponte C, Soriano F: Adherence

of streptococcus pneumoniae to polystyrene plates and epithelial cells and the antiadhesive potential of albumin and xylitol. Pediatr Res 2011, 69:23–27.PubMedCrossRef 16. Naves P, del Prado G, Huelves L, Rodriguez-Cerrato V, Ruiz V, Ponte MC, Soriano F: Effects of human serum albumin, ibuprofen and N-acetyl-L-cysteine

against biofilm formation by pathogenic Escherichia coli strains. J Hosp Infect 2010, 76:165–170.PubMedCrossRef 17. Hojo K, Nagaoka S, Ohshima T, Maeda N: Bacterial interactions in dental biofilm Oxalosuccinic acid development. J Dent Res 2009, 88:982–990.PubMedCrossRef 18. Wyss C: Growth of Porphyromonas gingivalis, Treponema denticola, T. pectinovorum, T. socranskii, and T. vincentii in a chemically defined medium. J Clin Microbiol 1992, 30:2225–2229.PubMed 19. Thurnheer T, Gmür R, Shapiro S, Guggenheim B: Mass transport of macromolecules within an in vitro model of supragingival plaque. Appl Environ Microbiol 2003, 69:1702–1709.PubMedCrossRef 20. Kesavalu L, Holt SC, Ebersole JL: Virulence of a polymicrobic complex, Treponema denticola and Porphyromonas gingivalis, in a murine model. Oral Microbiol Immun 1998, 13:373–377.CrossRef 21. Orth RK, O’Brien-Simpson NM, Dashper SG, Reynolds EC: Synergistic virulence of Porphyromonas gingivalis and Treponema denticola in a murine periodontitis model. Mol Oral Microbiol 2011, 26:229–240.PubMedCrossRef 22. Grenier D: Nutritional Interactions between Two Suspected Periodontopathogens, Treponema denticola and Porphyromonas gingivalis. Infect Immun 1992, 60:5298–5301.PubMed 23.