Whether the existence of a conscious God can be proved from the existence of the so called laws of nature
(i. e. fixed sequence of events) is a perplexing subject, on which I have often thought, but cannot see my way clearly…». Over and over again Darwin insisted that the issue PD-1/PD-L1 Inhibitor 3 mouse of spontaneous generation was intractable by the science of his time. As he wrote on November 21, 1866 to Julius Viktor Carus [www.darwinproject.ac.uk/] [Letter 5282], who was preparing a new edition of The Origin of Species, that, «My dear Sir […] I see that I have forgotten to say that you have my fullest consent to append any discussion which you may think fit to the new edition. As for myself I cannot believe in spontaneous generation & though I expect that at some future time the principle of life will be rendered intelligible, at present it seems to me beyond the confines of science». He was to maintain the same attitude for many years to come, as shown by the letter mailed on March 28, 1882, near the end of his life, to George Charles Wallich (de Beer 1959). In it Darwin wrote that, «My dear Sir, You expressed
quite correctly my views where you say that I had intentionally left the question of the Origin of Life uncanvassed as being altogether ultra vires in the CA4P mouse present state of our knowledge, & that I dealt only with the manner of succession. I have met with no evidence that seems in the least trustworthy, in favour of the so-called Spontaneous generation. I believe that I have somewhere said (but cannot find the passage) that the principle of continuity renders it probable that the principle of life will hereafter be shown to be a part, or consequence of some general law; but this is only conjecture and not science. I know nothing about the Protista, and shall be very glad to read your Lecture when it is published, if you will be so kind as to send me a copy. I remain, my dear Sir, Yours very faithfully Charles Darwin» Darwin’s
letter to Wallich expresses once more his reaction against the idea of life emerging from the decomposition of organic compounds. It is interesting, however, to recall a letter he sent on August 28, 1872 to Wallace, were Darwin wrote that ([Letter 8488], «[...] I should like to live to see Decitabine Archebiosis proved true, for it would be a discovery of transcendent importance; or, if false, I should like to see it disproved, and the facts otherwise explained; but I shall not live to see all this». Nor will we. Acknowledgements The assistance of Mr. Adam Perkins, archivist of the Darwin Archive at Cambridge University Library and Mme. Judith Magee, Collection Development Manager of the Natural History Museum Library is gratefully buy Geneticin acknowledged. The authors also wish to thank Paola Marco for her help to localize some of Darwin’s letters. The work reported here has been greatly facilitated by the documents available at The Darwin Correspondence Project (http://www.darwinproject.ac.